US 2,004,018,999 · Filed 2001-05-16

Methods and compositions for RNA interference

The present invention provides methods for attenuating gene expression in a cell using gene-targeted double stranded RNA (dsRNA). The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the “target” gene).

Patent details

Publication number
US 2,004,018,999
Filing date
2001-05-16
Grant date
Application — not yet granted
Assignee
David Beach / Emily Bernstein / Amy Caudy / Scott Hammond / Gregory Hannon
Inventor(s)
BEACH DAVID, BERNSTEIN EMILY, CAUDY AMY, HAMMOND SCOTT, HANNON GREGORY
CPC class
C12N15/1034

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