US 2004/0086884 · Filed 2003-01-24

Methods and compositions for RNA interference

The present invention provides methods for attenuating gene expression in a cell using gene-targeted double stranded RNA (dsRNA). The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the “target” gene).

Fig. 1. Illustration of a DNA double helix. Not this patent’s official drawing.

Patent details

Publication number
US 2004/0086884
Filing date
2003-01-24
Grant date
Application — not yet granted
Assignee
Genetica, Inc. / Cold Spring Harbor Laboratory
Inventor(s)
BEACH DAVID H., BERNSTEIN EMILY, CAUDY AMY, HAMMOND SCOTT, HANNON GREGORY J., PADDISON PATRICK J., CONKLIN DOUGLAS
CPC class
C12N15/1034

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