US 2010/0218264 · Filed 2009-12-03
Genome editing in rats using zinc-finger nucleases
Disclosed herein are methods and compositions for genome editing of one or more loci in a rat, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
Patent details
- Publication number
- US 2010/0218264
- Filing date
- 2009-12-03
- Grant date
- Application — not yet granted
- Assignee
- Sangamo Biosciences, Inc. / Sigma Aldrich Company
- Inventor(s)
- CUI XIAOXIA, GEURTS ARON M., URNOV FYODOR
- CPC class
- A01K67/0275
Want to file your own patent?
Run your idea through our free scanner — we’ll show you which existing patents are conceptually closest, including this one if it’s a match.
Free patentability scanRelated patents in this cluster
- US 5,633,425: Transgenic non-human animals capable of producing heterologous antibodies
- US 5,545,807: Production of antibodies from transgenic animals
- US 5,661,016: Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
- US 6,075,181: Human antibodies derived from immunized xenomice