US 4,873,316 · Granted 1989-10-10
Isolation of exogenous recombinant proteins from the milk of transgenic mammals
This invention relates to the production of recombinant proteins in mammals' milk. Particularly, this invention relates to an expression system comprising the mammal's casein promoter which when transgenically incorporated into a mammal permits the female species of that mammal to produce the desired recombinant protein in or along with its milk. This invention also relates to the transgenic mammal that produces the desired recombinant product in its milk.
Patent details
- Publication number
- US 4,873,316
- Filing date
- 1987-06-23
- Grant date
- 1989-10-10
- Assignee
- Biogen, Inc.
- Inventor(s)
- MEADE; HARRY, LONBERG; NILS
- CPC class
- C12N15/8509
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