US 5,175,383 Β· Granted 1992-12-29

Animal model for benign prostatic disease

A male transgenic mouse containing germ cells and somatic cells which contain a recombinant gene which is a vertebrate gene in the int-2/FGF family which is capable of promoting benign prostatic hyperplasia or hypertrophy in said transgenic mouse, said gene being introduced into the mouse, or an ancestor of the mouse, at an embryonic stage.

Patent details

Publication number
US 5,175,383
Filing date
1989-02-17
Grant date
1992-12-29
Assignee
President And Fellows Of Harvard College
Inventor(s)
LEDER; PHILIP, MULLER; WILLIAM J.
CPC class
C12N15/8509

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