US 5,721,367 Β· Granted 1998-02-24
Homologous recombination in mammalian cells
The invention relates to methods for intracellularly producing DNA segments by homologous recombination of smaller overlapping DNA fragments and transgenic mammalian cells and transgenic non-human mammals produced by such methods.
Patent details
- Publication number
- US 5,721,367
- Filing date
- 1995-06-05
- Grant date
- 1998-02-24
- Assignee
- Pharming B.V.
- Inventor(s)
- KAY; ROBERT M., BERNS; ANTON, KRIMPENFORT; PAUL, PIEPER; FRANK, STRIJKER; REIN
- CPC class
- A01K67/0275
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