US 7,148,054 · Granted 2006-12-12
Evolution of whole cells and organisms by recursive sequence recombination
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
Patent details
- Publication number
- US 7,148,054
- Filing date
- 2002-07-11
- Grant date
- 2006-12-12
- Assignee
- Maxygen, Inc.
- Inventor(s)
- DELCARDAYRE STEPHEN, TOBIN MATTHEW, STEMMER WILLEM P. C., NESS JON E., MINSHULL JEREMY, PATTEN PHILLIP, SUBRAMANIAN VENKITESWATAN, CASTLE LINDA A., KREBBER CLAUS M., BASS STEVE, ZHANG YING-XIN, COX TONY, HUISMAN GJALT, YUAN LING, AFFHOLTER JOSEPH A.
- CPC class
- C07K14/245
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