US 7,501,552 · Granted 2009-03-10

Transgenic non-human animals for producing chimeric antibodies

The invention relates to transgenic non-human animals capable of producing heterologous antibodies and methods for producing human sequence antibodies which bind to human antigens with substantial affinity.

Fig. 1. Illustration of a DNA double helix. Not this patent’s official drawing.

Patent details

Publication number
US 7,501,552
Filing date
2004-12-10
Grant date
2009-03-10
Assignee
Medarex, Inc.
Inventor(s)
LONBERG NILS, KAY ROBERT M.
CPC class
A01K67/0275

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