US 7,576,259 Β· Granted 2009-08-18

Method for making genetic modifications

Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.

Patent details

Publication number
US 7,576,259
Filing date
2007-09-27
Grant date
2009-08-18
Assignee
Regeneron Pharmaceuticals, Inc.
Inventor(s)
POUEYMIROU WILLIAM, DECHIARA THOMAS M., AUERBACH WOJTEK, FRENDEWEY DAVID, VALENZUELA DAVID M.
CPC class
A01K67/0271

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