US 7,659,442 · Granted 2010-02-09
Method for making homozygous genetic modifications
Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.
Patent details
- Publication number
- US 7,659,442
- Filing date
- 2007-09-27
- Grant date
- 2010-02-09
- Assignee
- Regeneron Pharmaceuticals, Inc.
- Inventor(s)
- POUEYMIROU WILLIAM, DECHIARA THOMAS M., AUERBACH WOJTEK, FRENDEWEY DAVID, VALENZUELA DAVID M.
- CPC class
- A01K67/0271
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